Home Catalog Vaccine Unistrain PRRS

Vaccine Unistrain PRRS

Species Pigs.
Composition

Each dose contains: Lyophilized pellet.  

Active substance:  
Live attenuated porcine reproductive and respiratory syndrome (PRRS) virus, strain VP-046 BIS – 10³·⁵ - 10⁵·⁵ CCID₅₀ *  
(*cell culture infectious doses).  

Solvent:  
Phosphate buffered solution.

Indications

Breeding females:  
The vaccine is intended for the active immunization of breeding females in farms affected by the European PRRS virus, with the aim of:  
- Reducing reproductive disorders;  
- Decreasing the incidence and duration of viremia;  
- Preventing transplacental transmission of the virus;  
- Reducing the viral load in tissues;  
- Mitigating clinical signs in piglets associated with infection by PRRS virus strains.  
In laboratory conditions, vaccination of sows has demonstrated a reduction in the negative impact of PRRS virus infection on piglet herd performance (mortality and weight gain) during the first 28 days of life.  
- Onset of immunity: 30 days after vaccination;  
- Duration of immunity: 16 weeks after vaccination.  

Piglets from 4 weeks of age: 
The vaccine is intended for the active immunization of piglets in farms affected by the European PRRS virus, with the objectives of:  
- Reducing clinical signs associated with PRRS virus contamination;  
- Decreasing the incidence and duration of viremia;  
- Reducing the duration of virus shedding by infected animals.  
In experimental conditions, vaccination has demonstrated a reduction in the viral load in lung tissue. In field conditions, it has been observed that, in the case of PRRS virus contamination during the fattening period, vaccination reduces mortality and the negative effects of the disease on average daily weight gain.  
- Onset of immunity: 28 days after vaccination;  
- Duration of immunity: 24 weeks after vaccination.

Dosage and method of administration

- For intramuscular or intradermal use:  
- Intramuscular route: Vaccination is performed in the neck area.  

- Intradermal route:  
- In pigs from 4 weeks of age, the vaccine is administered in the neck region;  
- In breeding females, the vaccine can be administered in the neck region, perineal area, or udder area.  

- Required equipment: 
An intradermal (ID) device provided by the marketing authorization holder or any other suitable needle-free device capable of delivering a 0.2 ml dose (with an injection stream diameter of 0.25–0.30 mm and a maximum injection force of 0.9–1.3 N) is used.  

- Precautions:  
Aseptic injection techniques must be strictly followed to prevent contamination during vaccine administration.  

- Doses and administration methods:  
Piglets from 4 weeks of age:
  
- 2 ml via intramuscular injection or 0.2 ml via intradermal administration.  

Breeding females:  
- 2 ml via intramuscular injection or 0.2 ml via intradermal administration.  
- A single vaccination is performed in each reproductive cycle to protect the subsequent gestation.  
- For gilts: 4 weeks before mating, administer one injection of the reconstituted vaccine to each animal.  
- For sows: Administer one injection of the reconstituted vaccine to each animal:  
  - 2 weeks before each mating, or  
  - In weeks 8–9 of each gestation (approximately 60 days after mating), or  
  - Vaccinate sows every 4 months.  

Caution: Sows uncontaminated with PRRSV or unvaccinated should not be vaccinated during gestation.  

Recommendations for correct administration:  
Reconstitute the vaccine using the appropriate solvent:
 

Solvent volume

Number of doses per vial

IM ID
10 doses 20 ml -
25 doses 50 ml -
50 doses 100 ml 10 ml
100 doses 200 ml 20 ml
125 doses 250 ml 25 ml
250 doses - 50 ml



If the solvent has been stored under refrigeration, allow the solvent to reach a temperature between 15 °C and 25 °C before reconstituting the lyophilized pellet.  
Remove the aluminum cap from the solvent vial and aspirate to extract the contents of the vial. Then inject this amount of solvent into the vial containing the lyophilized vaccine. Shake the vial until the lyophilized pellet is completely dissolved. After the vial containing the remaining solvent.  
Shake well before use. The reconstituted vaccine is a homogeneous reddish solution. Avoid contamination during reconstitution and use. For administration, use only sterile needles and syringes.  
For simultaneous administration with ERYSENG PARVO in breeding females starting from 6 months of age, the UNISTRAIN PRRS product combined with ERYSENG PARVO should only be administered if the animals have been vaccinated prior to mating.  
The following instructions must be followed: the contents of a single vial of UNISTRAIN PRRS must be combined with the contents of a single vial of ERYSENG PARVO, as described for combining with solvent. Administer a single intramuscular dose (2 ml) of the combined vaccine within a maximum of 2 hours from mixing.  

UNISTRAIN PRRS:
- 10 doses  
- 25 doses  
- 50 doses  

ERYSENG PARVO: 
- 10 doses (20 ml)  
- 25 doses (50 ml)  
- 50 doses (100 ml)

Contraindications

- Do not use in cases of hypersensitivity to the active substance or any of the excipients.  
- Do not administer to herds where the presence of the European PRRS virus has not been confirmed by appropriate virological diagnostic methods.  
- No information is available regarding the safety of the vaccine’s use on the reproductive performance of males.

Waiting period

Zero days.

Release form

Intramuscular use:  
- Cardboard box with 1 vial of lyophilizate containing 10 doses and 1 vial with 20 ml solvent.  
- Cardboard box with 1 vial of lyophilizate containing 25 doses and 1 vial with 50 ml solvent.  
- Cardboard box with 1 vial of lyophilizate containing 50 doses and 1 vial with 100 ml solvent.  
- Cardboard box with 1 vial of lyophilizate containing 100 doses and 1 vial with 200 ml solvent.  
- Cardboard box with 1 vial of lyophilizate containing 125 doses and 1 vial with 250 ml solvent.  
- Cardboard box with 10 vials of lyophilizate containing 10, 25, 50, 100, or 125 doses.  
- Cardboard box with 10 vials with 20, 50, 100, 200, or 250 ml solvent.  

Intradermal use:
- Cardboard box with 1 vial of lyophilizate containing 50 doses and 1 vial with 10 ml solvent.  
- Cardboard box with 1 vial of lyophilizate containing 100 doses and 1 vial with 20 ml solvent.  
- Cardboard box with 1 vial of lyophilizate containing 125 doses and 1 vial with 25 ml solvent.  
- Cardboard box with 1 vial of lyophilizate containing 250 doses and 1 vial with 50 ml solvent.  
- Cardboard box with 10 vials of lyophilizate containing 50, 100, 125, or 250 doses.  
- Cardboard box with 10 vials with 10, 20, 25, or 50 ml solvent.  

*Not all package sizes may be marketed.

Storage conditions

Lyophilized pellet: Store and transport under refrigeration (2°C – 8°C). Do not freeze. Protect from light.  
Solvent: Store and transport at a temperature below 25°C. Do not freeze. Protect from light.

Shelf life

2 years from the date of manufacture.  
Shelf life after reconstitution with solvent: 4 hours.  
Shelf life after combination with ERYSENG PARVO: 2 hours.

Do not use after the expiry date indicated on the packaging.