CircoMax Myco

Pigs (for fattening).

Each 2 ml dose contains:  

Active substances:  
- Inactivated recombinant chimeric porcine circovirus type 1 containing open reading frame 2 (ORF2) protein of porcine circovirus type 2a – 1.5 - 4.9 PR*  
- Inactivated recombinant chimeric porcine circovirus type 1 containing ORF2 protein of porcine circovirus type 2b – 1.5 - 5.9 PR*  
- Inactivated Mycoplasma hyopneumoniae, strain P-5722-3 – 1.5 - 4.7 PR*  

Adjuvant:  
- MetaStim containing:  
  - Squalene 0.4% (v/v)  
  - Poloxamer 401 0.2% (v/v)  
  - Polysorbate 80 0.032% (v/v)  

*Relative potency unit determined by ELISA antigen quantification (in vitro potency test) compared to a reference vaccine.  

Excipients:  
- Anhydrous monobasic potassium phosphate  
- Sodium chloride  
- Potassium chloride  
- Anhydrous disodium phosphate  
- Sodium phosphate dibasic heptahydrate  
- Sodium tetraborate decahydrate  
- Tetrasodium EDTA  
- Water for injection

- Active immunization of pigs against porcine circovirus type 2 (PCV2) to reduce viral load in blood and lymphoid tissues, virus shedding in feces, and lymphoid tissue lesions associated with PCV2 infection. Demonstrated protection against PCV2a, PCV2b, and PCV2d.  
- Active immunization of pigs against Mycoplasma hyopneumoniae to reduce lung lesions associated with Mycoplasma hyopneumoniae infection.  

Onset of immunity (both vaccination schedules): 3 weeks after the last vaccination.  
Duration of immunity (both vaccination schedules): 23 weeks after the last vaccination.  

Vaccination also reduces body weight loss under field conditions.

Pig Vaccination:

- Intramuscular Vaccination:  
  Administer in the neck, behind the ear.  

- Single-Dose Vaccination Schedule:  
  A single 2 ml dose for pigs starting from 3 weeks of age.  

- Split-Dose Vaccination Schedule:  
  Two injections of 1 ml each, starting from 3 days of age, with an interval of approximately 3 weeks.  

Recommendations for Proper Administration: 
- The choice of dosing regimen, including vaccination age, should consider farm-specific conditions.  
- In cases of moderate to high maternal antibody levels against PCV2, the split-dose schedule or delayed vaccination is recommended.  
- Shake well before administration and intermittently during vaccination.  
- Use a multi-dose syringe or needle-free device for intramuscular injections.  
- Follow the manufacturer’s instructions for vaccination devices.  
- For needle-free administration, use a device suitable for 2 ml intramuscular injections in pigs from 3 weeks of age, ensuring correct pressure, handling, and cleaning procedures.  
- Follow the manufacturer's age or weight restrictions.  
- The vaccine must be administered under aseptic conditions.  

Storage: 
- A slight black deposit and phase separation may occur during storage.  
- After shaking, the deposit disappears, and the emulsion becomes homogeneous again.

Zero days.

- High-density polyethylene (HDPE) bottles of 50 ml, 100 ml, and 250 ml, with a chlorobutyl elastomer stopper, sealed with an aluminum cap.  
- Carton boxes containing:  
  - 1 bottle of 50 ml, 100 ml, or 250 ml.  
  - 10 bottles of 50 ml or 100 ml.  
  - 4 bottles of 250 ml.  

*Not all packaging sizes may be commercially available.

2 years from the date of production, from the first opening – 3 months.

Do not use after the expiry date indicated on the packaging.