Bovilis Bovipast RSP

Cattle from the age of approximately 2 weeks.

Active substance:  
- Inactivated bovine respiratory syncytial virus: 10⁵.⁵ TCID₅₀*  
- Inactivated Parainfluenza - 3 virus: 10⁷.³ TCID₅₀*  
- Inactivated Mannheimia haemolytica: 9 x 10⁹ cells  

*Antigen concentration that induces an antibody titer in rabbits not significantly lower than a standard preparation; TCID₅₀ = 50% infectious dose in cell cultures.

Adjuvants:  
- Aluminum hydroxide: 37.5 mg  
- Quil A (Saponin): 0.625 mg  

Excipients:  
- Thimerosal: 0.05 mg  

For active immunization of cattle against:  
- Parainfluenza-3 virus: to reduce infection.  
- Bovine Respiratory Syncytial Virus (BRSV): to reduce infection and clinical signs.  
- Mannheimia haemolytica, serotype A1: to reduce infection, mortality, clinical signs, pulmonary lesions, and bacterial invasion of the lungs caused by serotypes A1 and A6.  

Cross-immunity against Mannheimia haemolytica, serotype A6, was demonstrated in a controlled infection experiment under laboratory conditions, following primary vaccination.  

It has been demonstrated that:  
- Active immunity to BRSV and Parainfluenza-3 virus persists for at least 6 and 4 months, respectively, after primary immunization.  
- Protective immunity to Mannheimia haemolytica persists for at least 6 weeks after primary immunization.  
- Immunity establishment: 2 weeks.

Dose: 5 ml

Administration method: Subcutaneous injection in the neck region.

Primary immunization: Bovine young approximately 2 weeks old should be vaccinated twice at an interval of approximately 4 weeks.

Revaccination:
If revaccination is required, administer a single dose 2 weeks before the risk period, such as transport, introduction into the herd, or shelter change.

The vaccine must be shaken well before administration.
For vaccine administration, it is recommended to use needles with a diameter of 15-20 mm and a length of 10-18 mm. The vaccine should be brought to room temperature before use and injected quickly.

Do not vaccinate animals with concurrent diseases, heavily infested with parasites, or in poor general condition, as a satisfactory immune response is only achieved in healthy, immunocompetent animals.

Zero days.

50 ml glass vials of type I (Ph Eur), sealed with type I rubber stoppers (Ph Eur) and aluminum caps.

Secondary packaging: Cardboard box with 1 vial x 50 ml.

28 months from the date of manufacture, 10 hours from the first opening.

Do not use after the expiry date indicated on the packaging.