Depo-Promone 50mg/ml

DEPO-PROMONE- injectable suspension for bitches.

Active substance(s): Medroxyprogesterone acetate- 50 mg

List of excipients:

Propyl parahydroxybenzoate- 0.14 mg

Methyl parahydroxybenzoate- 1.30 mg

DEPO-PROMONE is recommended for the prevention of estrus in bitches in the following situations:

1. High-risk bitches:
- Bitches for whom mounting or giving birth involves a very high risk to the animal's life.
- Bitches presenting a high surgical risk in the case of ovariohysterectomy. It is important to note that some of these bitches may require subsequent surgery, for which reason the section on contraindications and warnings should be consulted.

2. Longevity extension:
- DEPO-PROMONE can offer these bitches the possibility of extending their lifespan without causing estrus disorders or undesirable consequences on pregnancy.

3. Gestation management:
- Bitches in whom gestation is not desired.
- Bitches in whom gestation is optional, for whom the administration of DEPO-PROMONE is recommended to extend the date of establishment of a new pregnancy.

It is not recommended for female dogs from which offspring are desired (those in the kennel).

Progesterone stimulates the proliferation and secretory activity of the endometrium in female dogs. In female dogs treated and untreated with Depo-Promone, this response is usually temporary, but in some females, it may persist, leading to an enlarged uterus or unacceptable accumulation of mucus in the uterus, vaginal discharge, and may be associated with the development of pyometra. Thus, Depo-Promone is contraindicated in bitches in the following situations:

Proestrus, estrus, or metestrus;

Young females, before their first estrus;

Pregnant females;

History of genito-urinary conditions;

Abnormal and persistent vaginal discharge;

Nymphomania or abnormal estrus periods;

False pregnancy;

Mammary tumors that may be stimulated by progesterone activity;

Other detectable abnormalities of the endocrine or reproductive system.

Type I colorless glass vial of 3 ml or 5 ml with bromobutyl rubber stopper.

Cardboard box with a bottle of 3 ml or 5 ml.

Shelf life of the veterinary medicinal product as packaged for sale: 60 months

Shelf life after first opening the primary packaging: 28 days

Do not use after the expiry date indicated on the packaging