Vaccine Nobivac DHPPi

1 dose of 1 ml contains:
Active substance:
- Live Carre disease virus (CDV) strain Onderstepoort – minimum 10^4.0 TCID₅₀ - maximum 10^6.0 TCID₅₀
- Live canine adenovirus type 2 (CAV2) strain Manhattan LPV3 – minimum 10^4.0 TCID₅₀ - maximum 10^6.5 TCID₅₀
- Live canine parvovirus (CPV) strain 154 – minimum 10^7.0 TCID₅₀ - maximum 10^8.4 TCID₅₀
- Canine parainfluenza virus (CPi) Cornell strain - minimum 10^5.5 TCID₅₀ – maximum 10^7.0 TCID₅₀

Excipients:
The vaccine: Sorbitol, hydrolyzed gelatin, disodium phosphate dihydrate, water for injections (before lyophilization).
Solvent: disodium phosphate dihydrate, potassium phosphate dihydrogen, water for injections.
The freeze-dried fraction is a white pellet and the solvent (and the reconstituted product) is a slightly opalescent suspension.

For active immunization of dogs in order to prevent clinical signs and mortality caused by infection with Carre's disease virus, canine parvovirus, canine adenovirus and canine parainfluenza virus and prevention of viral excretion caused by infection with canine parvovirus and canine adenovirus.

The onset of immunity is approximately one week after vaccination and lasts for 3 years. The onset of immunity for CPi is from about 4 weeks and lasts for a year after vaccination.

The contents of a vial of reconstituted vaccine will be injected subcutaneously. The vaccine is reconstituted with the contents of one vial (1.0 ml) of Nobivac Lepto, one vial (1.0 ml) of Nobivac Rabies, one vial (1.0 ml) of Nobivac RL, or one vial (1.0 ml) of Nobivac Diluant.

The preferred age for vaccination against hepatitis (CAV1), CAV2 infection and parainfluenza virus infection is 8-12 weeks because it is the minimum age at which maternally derived residual antibodies have reached levels that can no longer interfere with the immune response. The optimal age for vaccination of puppies against distemper and parvovirus is the minimum age at which maternally derived residual antibodies have reached levels that can no longer interfere with the immune response. In most cases, this age is between 6 and 9 weeks, but to ensure the protection of puppies with very high levels of maternal antibodies, it is recommended that the final vaccination against these 2 diseases takes place around 12 weeks of age. The following recommendations are included considering that immunization with Nobivac DHPPi is part of a complex vaccination program.

a. Program for puppies possibly exposed to distemper/parvo infection before the age of 8-9 weeks; and ADM status is unknown:
4-6 weeks - Nobivac Parvo-C or Nobivac Puppy DP
8-9 weeks - Nobivac DHPPi with Nobivac Lepto
12 weeks - Nobivac DHPPi with Nobivac Lepto, Nobivac Rabies or Nobivac RL

b. Program for puppies whose vaccination starts at the age of 8-9 weeks:
8-9 weeks - Nobivac DHPPi with Nobivac Lepto
12 weeks - Nobivac DHPPi with Nobivac Lepto, Nobivac Rabies or Nobivac RL

c. Program for puppies whose vaccination does not start before the age of 12 weeks:
12 weeks - Nobivac DHPPi with Nobivac Lepto, Nobivac Rabies or Nobivac RL
14-15 weeks – NobivacLepto.

Reminder:
Revaccination is recommended as follows:
1. Carre disease, infectious hepatitis, canine parvovirus – every 3 years
2. Canine parainfluenza virus infection – every year.

Only healthy dogs will be vaccinated and for this an appropriate clinical examination will be made before administration. After vaccination, contact with potential sources of infection will be avoided for a period of 14 days.
Sterile equipment will be used for vaccination, avoiding at the same time contamination of the vaccine with traces of disinfectant.

Zero zile.

2 years from the date of production, from the first opening – 30 minutes.

Do not use after the expiry date indicated on the packaging.