Vaccine Nobilis IBmulti+ND+EDS

Active substances per 0.5 ml dose:

* Infectious Bronchitis Virus, inactivated, strain M41: 4.0 log₂ VN units
* Infectious Bronchitis Virus, inactivated, strain 249G: 4.0 log₂ VN units
* Egg Drop Syndrome Virus, inactivated, strain BC14: 6.5 log₂ HI units
* Newcastle Disease Virus, inactivated, strain Clone 30:

* 4.0 log₂ HI units per 1/50 of the dose or
* 50 PD₅₀ (units measured by potency tests per dose, according to the European Pharmacopoeia)

Excipients:

* Liquid paraffin
* Polysorbate
* Sorbitan oleate
* Glycine.

• Preventing the decrease in egg production produced by the Infectious Bronchitis virus serotype Massachusetts and reducing the infection in birds
• Prevention of mortality and clinical signs produced by the Pseudofowl Plague virus;
• Prevention of the decrease in egg production caused by the infection with the Egg Fall Syndrome virus Active immunity develops in 4 weeks and is maintained during a laying period (for the diseases caused by the Infectious Bronchitis virus and the Pseudoplague virus, a first vaccination with appropriate live vaccines is required against these pathogens during the growing season).

Nobilis IBmulti+ND+EDS should be administered to birds around 14-20 weeks of age, but not less than 4 weeks before the expected period for laying. Live vaccines against infectious bronchitis and Newcastle disease are administered for the first time, unless serological tests indicate otherwise. The interval between the first vaccination and booster should not be less than 4 weeks and preferably more than 6 weeks.
Dose: 0.5 ml of vaccine per bird by intramuscular injection into the leg or chest muscle or by subcutaneous injections, on the dorsal side of the neck, using medium-sized needles (20g x ½”).

Before use, the vaccine will be allowed to reach room temperature (15 - 25°C). Occasionally, the vaccine may separate into two layers. This does not affect the biological value in any way. Shake the bottle well before use and periodically during use. An automatic injection system incorporating a device that ensures correct administration and prevents possible contamination of the vaccine must be used for administration. Make sure the equipment is clean and sterile before use. Vaccination equipment with rubber parts shall not be used, as the excipient may attack certain types of rubber

Zero days.

2 years from the date of production, after reconstitution – 3 hours.

Do not use after the expiry date indicated on the packaging.